“单光子探测器阵列”相关最新SCI收录(3)
时间: 2015-10-09   来源:   作者:   点击: 22
第 1 条,共 4 条
标题: 0.5 billion events per second time correlated single photon counting using CMOS SPAD arrays
作者: Krstajic, N (Krstajic, Nikola); Poland, S (Poland, Simon); Levitt, J (Levitt, James); Walker, R (Walker, Richard); Erdogan, A (Erdogan, Ahmet); Ameer-Beg, S (Ameer-Beg, Simon); Henderson, RK (Henderson, Robert K.)
来源出版物: OPTICS LETTERS  卷: 40  期: 18  页: 4305-4308  DOI: 10.1364/OL.40.004305  出版年: SEP 15 2015  
摘要: We present a digital architecture for fast acquisition of time correlated single photon counting (TCSPC) events from a 32 x 32 complementary metal oxide semiconductor (CMOS) single photon avalanche detector (SPAD) array (Megaframe) to the computer memory. Custom firmware was written to transmit event codes from 1024-TCSPC-enabled pixels for fast transfer of TCSPC events. Our 1024-channel TCSPC system is capable of acquiring up to 0.5 x 10(9) TCSPC events per second with 16 histogram bins spanning a 14 ns width. Other options include 320 x 10(6) TCSPC events per second with 256 histogram bins spanning either a 14 or 56 ns time window. We present a wide-field fluorescence microscopy setup demonstrating fast fluorescence lifetime data acquisition. To the best of our knowledge, this is the fastest direct TCSPC transfer from a single photon counting device to the computer to date. (C) 2015 Optical Society of America
入藏号: WOS:000361556700030
地址: [Krstajic, Nikola; Walker, Richard; Erdogan, Ahmet; Henderson, Robert K.] Univ Edinburgh, Inst Integrated Micro & Nano Syst, Sch Engn, Edinburgh, Midlothian, Scotland. 
[Krstajic, Nikola] Queens Med Res Inst, MRC Ctr Inflammat Res, EPSRC IRC Hub Opt Mol Sensing & Imaging, Edinburgh, Midlothian, Scotland. 
[Poland, Simon; Levitt, James; Ameer-Beg, Simon] Kings Coll London, Div Canc Studies, London, England. 
[Poland, Simon; Levitt, James; Ameer-Beg, Simon] Kings Coll London, Randall Div Cell & Mol Biophys, London, England. 
[Walker, Richard] Photon Force Ltd, Edinburgh, Midlothian, Scotland.
通讯作者地址: Krstajic, N (通讯作者),Univ Edinburgh, Inst Integrated Micro & Nano Syst, Sch Engn, Edinburgh, Midlothian, Scotland.
电子邮件地址: n.krstajic@physics.org
ISSN: 0146-9592
eISSN: 1539-4794

第 2 条,共 4 条
标题: Fast single photon avalanche photodiode-based time-resolved diffuse optical tomography scanner
作者: Mu, Y (Mu, Ying); Niedre, M (Niedre, Mark)
来源出版物: BIOMEDICAL OPTICS EXPRESS  卷: 6  期: 9  页: 3596-3609  DOI: 10.1364/BOE.6.003596  出版年: SEP 1 2015  
摘要: Resolution in diffuse optical tomography (DOT) is a persistent problem and is primarily limited by high degree of light scatter in biological tissue. We showed previously that the reduction in photon scatter between a source and detector pair at early time points following a laser pulse in time-resolved DOT is highly dependent on the temporal response of the instrument. To this end, we developed a new single-photon avalanche photodiode (SPAD) based time-resolved DOT scanner. This instrument uses an array of fast SPADs, a femto-second Titanium Sapphire laser and single photon counting electronics. In combination, the overall instrument temporal impulse response function width was 59 ps. In this paper, we report the design of this instrument and validate its operation in symmetrical and irregularly shaped optical phantoms of approximately small animal size. We were able to accurately reconstruct the size and position of up to 4 absorbing inclusions, with increasing image quality at earlier time windows. We attribute these results primarily to the rapid response time of our instrument. These data illustrate the potential utility of fast SPAD detectors in time-resolved DOT. (C) 2015 Optical Society of America
入藏号: WOS:000360888400041
地址: [Mu, Ying; Niedre, Mark] Northeastern Univ, Dana Res Ctr, Dept Elect & Comp Engn, Boston, MA 02115 USA.
通讯作者地址: Mu, Y (通讯作者),Northeastern Univ, Dana Res Ctr, Dept Elect & Comp Engn, Boston, MA 02115 USA.
电子邮件地址: mu.y@husky.neu.edu; mniedre@ece.neu.edu
ISSN: 2156-7085

第 3 条,共 4 条
标题: Bowtie filters for dedicated breast CT: Analysis of bowtie filter material selection
作者: Kontson, K (Kontson, Kimberly); Jennings, RJ (Jennings, Robert J.)
来源出版物: MEDICAL PHYSICS  卷: 42  期: 9  页: 5270-5277  DOI: 10.1118/1.4928476  出版年: SEP 2015  
摘要: Purpose: For a given bowtie filter design, both the selection of material and the physical design control the energy fluence, and consequently the dose distribution, in the object. Using three previously described bowtie filter designs, the goal of this work is to demonstrate the effect that different materials have on the bowtie filter performance measures. 
Methods: Three bowtie filter designs that compensate for one or more aspects of the beam-modifying effects due to the differences in path length in a projection have been designed. The nature of the designs allows for their realization using a variety of materials. The designs were based on a phantom, 14 cm in diameter, composed of 40% fibroglandular and 60% adipose tissue. Bowtie design #1 is based on single material spectral matching and produces nearly uniform spectral shape for radiation incident upon the detector. Bowtie design #2 uses the idea of basis-material decomposition to produce the same spectral shape and intensity at the detector, using two different materials. With bowtie design #3, it is possible to eliminate the beam hardening effect in the reconstructed image by adjusting the bowtie filter thickness so that the effective attenuation coefficient for every ray is the same. Seven different materials were chosen to represent a range of chemical compositions and densities. After calculation of construction parameters for each bowtie filter design, a bowtie filter was created using each of these materials (assuming reasonable construction parameters were obtained), resulting in a total of 26 bowtie filters modeled analytically and in the PENELOPE Monte Carlo simulation environment. Using the analytical model of each bowtie filter, design profiles were obtained and energy fluence as a function of fan-angle was calculated. Projection images with and without each bowtie filter design were also generated using PENELOPE and reconstructed using FBP. Parameters such as dose distribution, noise uniformity, and scatter were investigated. 
Results: Analytical calculations with and without each bowtie filter show that some materials for a given design produce bowtie filters that are too large for implementation in breast CT scanners or too small to accurately manufacture. Results also demonstrate the ability to manipulate the energy fluence distribution (dynamic range) by using different materials, or different combinations of materials, for a given bowtie filter design. This feature is especially advantageous when using photon counting detector technology. Monte Carlo simulation results from PENELOPE. show that all studied material choices for bowtie design #2 achieve nearly uniform dose distribution, noise uniformity index less than 5%, and nearly uniform scatter-to-primary ratio. These same features can also be obtained using certain materials with bowtie designs #1 and #3. 
Conclusions: With the three bowtie filter designs used in this work, the selection of material is an important design consideration. An appropriate material choice can improve image quality, dose uniformity, and dynamic range. (C) 2015 American Association of Physicists in Medicine.
入藏号: WOS:000360645000027
地址: [Kontson, Kimberly] Univ Maryland, Dept Bioengn, College Pk, MD 20742 USA. 
US FDA, Div Imaging & Appl Math, Off Sci & Engn Labs, Ctr Devices & Radiol Hlth, Silver Spring, MD 20993 USA.
通讯作者地址: Kontson, K (通讯作者),Univ Maryland, Dept Bioengn, College Pk, MD 20742 USA.
电子邮件地址: Kimberly.Kontson@fda.hhs.gov
ISSN: 0094-2405

第 4 条,共 4 条
标题: Nanobridge SQUIDs as calorimetric inductive particle detectors
作者: Gallop, J (Gallop, John); Cox, D (Cox, David); Hao, L (Hao, Ling)
来源出版物: SUPERCONDUCTOR SCIENCE & TECHNOLOGY  卷: 28  期: 8  文献号: 084002  DOI: 10.1088/0953-2048/28/8/084002  出版年: AUG 2015  
摘要: Superconducting transition edge sensors (TESs) have made dramatic progress since their invention some 65 years ago (Andrews et al 1949 Phys. Rev. 76 154-155; Irwin and Hilton 2005 Topics Appl. Phys. 99 63-149) until now there are major imaging arrays of TESs with as many as 7588 separate sensors. These are extensively used by astronomers for some ground-breaking observations (Hattori et al 2013 Nucl. Instrum. Methods Phys. Res. A 732 299-302). The great success of TES systems has tended to overshadow other superconducting sensor developments. However there are other types (Sobolewski et al 2003 IEEE Trans. Appl. Supercond. 13 1151-7; Hadfield 2009 Nat. Photonics 3 696-705) which are discussed in papers within this special edition of the journal. Here we describe a quite different type of detector, also applicable to single photon detection but possessing possible advantages (higher sensitivity, higher operating temperature) over the conventional TES, at least for single detectors.
入藏号: WOS:000360930500004
地址: [Gallop, John; Cox, David; Hao, Ling] Natl Phys Lab, Teddington TW11 0LW, Middx, England. 
[Cox, David] Univ Surrey, Adv Technol Inst, Guildford GU2 5XH, Surrey, England.
通讯作者地址: Gallop, J (通讯作者),Natl Phys Lab, Hampton Rd, Teddington TW11 0LW, Middx, England.
电子邮件地址: ling.hao@npl.co.uk
ISSN: 0953-2048
eISSN: 1361-6668